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When people mention contemporary medicine, accuracy plays one of the most significant roles and people’s lives are directly dependent on it. Likewise, any researches related to medicine are necessary to comply with the highest standards. The problem nowadays is that any conclusions of researches can be posted online and used as a reference without being properly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and decided to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality measure. That allows both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores above 100 a

In a case presentation paper, Encyclopedic Tumor Analysis guided researchers in identifying HER2 overexpression in a patient with distal common bile duct carcinoma and in personalizing his treatment regimen. oncotarget research Microscopic ductal cell carcinoma. Adenonocarcinoma from human breast cancer tissue. Magnification 400X Microscopic ductal cell carcinoma. Adenonocarcinoma from human breast cancer tissue. Magnification 400X The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. oncotarget journal impact factor Researchers from multiple highly-regarded institutions located in India and from the Medical College of Wisconsin in the United states wrote a paper on the case presentation: “Liquid biopsy and multi-analyte testing guided trea

When public refer to modern medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to comply with the highest standards. The issue nowadays is that any results of researches can be posted online and used as a reference without being properly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores higher than 10

A promising new treatment option for the coronavirus was studied using a COVID-19 pseudovirus approach to observe its immune response to MEK inhibitors. Hospital As researchers around the world are in the midst of searching for treatment options capable of combatting the COVID-19 virus, a single solution will not be effective for everyone—in both a logistical and biological sense. To produce different treatment options for populations of varying age and immune system health, numerous avenues are currently being explored. Oncotarget One potential treatment, studied by a coalition of researchers from Brown University, the Fox Chase Cancer Center, and Verastem Oncology, used a COVID-19 pseudovirus approach to demonstrate immune response to MEK inhibitors in a level 2 biosafe environment. The paper detailing this study has been published at Oncotarget.com. “For the current study, we have developed a pseudotyped SARS-CoV-2 virus which has a lentiviral core but with the SARS-CoV-2 spik

When people discuss contemporary medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Hereby, any researches related to medicine are necessary to comply with the highest standards. The problem today is that any results of researches can be shared online and used as a reference without being properly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this challenge and decided to create an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores above 100 as well as r

When people discuss contemporary medicine, accuracy plays one of the most crucial roles and people’s lives are literally dependent on it. Hence, any researches related to medicine are required to comply with the top standards. The problem today is that any conclusions of researches can be shared online and used as a reference without being adequately verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and attempted to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective scores higher t

A genome-wide analysis of DNA methylation concluded that the TBX15 gene is hypermethylated and downregulated in tumors of patients with hepatocellular carcinoma. Listen to an audio version of this article Hepatocellular carcinoma is considered rare, though, it is also the most common primary tumor of the liver. Fortunately, most patients do not suffer from symptoms in the earlier stages of this disease. Unfortunately, patients diagnosed with late-stage hepatocellular carcinoma often present with symptoms caused by an underlying liver disease. “Hepatocellular carcinoma (HCC) is the sixth most prevalent human cancer and third-highest cause of cancer-related deaths worldwide, and its incidence is significantly increasing [1, 2].” Due to the high rate of post-treatment HCC relapse and metastasis, researchers based out of Japan—from the Institute of Biomedical Sciences at Tokushima University, Kumamoto University, and Kyushu University Beppu Hospital—conducted a full-genome analysis of

When public refer to today’s medicine, accuracy plays one of the most important roles and people’s lives are literally dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the top standards. The challenge today is that any recommendations of researches can be posted online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores higher

Researchers from Columbia University demonstrate that, in mouse-model melanoma, the therapeutic efficacy of unmodified anti-tumor antibodies is increased by combined immune checkpoint blockades and MEK inhibition. Melanoma, a cancer developing from pigment-containing cells melanocytes, light micrograph, photo under microscope Melanoma, a cancer developing from pigment-containing cells melanocytes, light micrograph, photo under microscope Melanoma is a highly prevalent human skin disease worldwide and, surprisingly, as much as 30% of all melanoma cases are a result of factors other than exposure to the sun or other ultraviolet light. The causes of such cases are still unknown to researchers, but some suggest the answers may lie in heredity. In the United States, one in five people will be diagnosed with melanoma by age 70. Doctors have observed relative success in patient outcomes when treating melanoma and other cancers with specific anti-tumor antibodies. However, the researchers in

When general population mention modern medicine, precision plays one of the most significant roles and human lives are directly dependent on it. Hereby, any researches pertaining to medicine are required to comply with the highest standards. The issue today is that any recommendations of researches can be published online and used as a reference without being adequately checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with re

When public mention modern medicine, accuracy plays one of the most crucial roles and people’s lives are directly dependent on it. Hence, any researches pertaining to medicine are necessary to comply with the top standards. The challenge nowadays is that any outcomes of researches can be shared online and used as a reference without being adequately verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and decided to create an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That helps both readers and authors to quality-check publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with respective scores higher than 100 a

Drug pricing is a big issue in the news, and there is continued controversy surrounding the major differences in patented cancer drug prices around the world. However, the patterns of affordability of these drugs are poorly understood. And although cancer care is undergoing a revolution with the arrival of new therapies such as immunotherapy, monoclonal antibodies, and targeted therapy, prices for cancer drugs vary widely. San Diego hospitals Dallas hospitals San Jose hospitals A recent study in Oncotarget, 2017, Vol. 8, Issue 42, by Jonathon Clark, Daniel A. Goldstein and others entitled “A global comparison of the cost of patented cancer drugs in relation to global differences in wealth” compared patterns of affordability of cancer drugs in Australia, China, India, Israel, South Africa, the United Kingdom, and the United States to assess whether affordability corresponded to other economic indicators.

When public mention contemporary medicine, accuracy plays one of the most significant roles and human lives are literally dependent on it. Hence, any researches pertaining to medicine are necessary to comply with the highest standards. The problem nowadays is that any conclusions of researches can be shared online and used as a reference without being adequately verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and decided to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality indicator. That helps both readers and authors to quality-check publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with respective scores abo

Researchers demonstrate the overexpression of the protein APOBEC3B and identify the transcription factor that directly regulates it, known as GATA3. Adrenal glands and a right-side adrenocortical carcinoma Adrenal glands and a right-side adrenocortical carcinoma Adrenocortical carcinoma (ACC) is a rare and aggressive cancer that forms above the kidneys in the outer layer of the adrenal gland tissue. According to the National Institutes of Health, the occurrence of ACC in the United States is believed to only affect one to two people per million, per year. This highly-rare disease also challenges patients and researchers due to its post-diagnosis five-year survival rate of a mere 51%. At this time, there are no known external factors that cause this disease. Most adrenocortical tumors that have been found produce symptoms including abdominal pain and higher levels of certain hormones, inclusive of cortisol, aldosterone, testosterone, and estrogen. Any of these hormones produced in exc

When public refer to contemporary medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are necessary to meet the top standards. The issue today is that any conclusions of researches can be shared online and used as a reference without being precisely verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and tried to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality indicator. That assists both readers and authors to validate publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores above 100 as well a

When general population refer to today’s medicine, precision plays one of the most significant roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are necessary to meet the top standards. The challenge nowadays is that any outcomes of researches can be posted online and used as a reference without being adequately verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with corresponding s

Researchers from Colorado published a study identifying potential mechanisms involved in the higher rate of metastasis in Ewing’s sarcoma. 3D DNA strand render with magnifying glass As the second most common bone and soft tissue cancer in children and young adults, Ewing’s sarcoma is an aggressive pediatric disease notorious for its high rate of metastasis and poor patient outcomes. Researchers from the University of Colorado in Aurora, Colorado, USA, published a paper in Oncotarget—a world-class and free-to-read scientific journal—detailing their study providing the first evidence of a cancer-promoting role for the PHF2 gene, among KDM5A and other genes responsible for promoting metastasis in Ewing’s sarcoma. EWS/Fli1 in “Low State” In preceding studies, researchers identified the role of the fused protein (previously two independent genes) EWS/Fli1 as a driver in 90% of Ewing’s sarcoma gene repression, cancer cell proliferation, survival, oncogenic transformation, and tumor growt

When people speak of modern medicine, precision plays one of the most crucial roles and people’s lives are directly dependent on it. Hereby, any researches pertaining to medicine are required to meet the top standards. The problem today is that any conclusions of researches can be posted online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality indicator. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective scores higher than 100 as well a

French and Italian researchers designed a study to improve treatment options for patients with clear-cell renal-cell carcinoma (ccRCC) at intermediate-risk by better characterizing their classification. RCC Renal Cell Carcinoma Written on Green Key of Metallic Keyboard. Finger pressing key. Listen to an audio version of this article A treatment plan for patients with cancer depends acutely on the current stage and progression rate it is discovered in, as well as the type of cancer it is. The more precisely a patients’ risk can be assessed, the more exact their treatment plan can be. This leads directly to better patient outcomes. One way to gauge a patients’ risk is to use a risk-stratified method. Risk stratification is the systematic classification of patients based on the current status of their health and the number of negative clinical prognostic factors that they present with. From Gustave Roussy, the Gustave Roussy Institute, and the University of Paris-Saclay—each in Villejui

When people discuss today’s medicine, precision plays one of the most significant roles and people’s lives are directly dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the highest standards. The challenge today is that any recommendations of researches can be published online and used as a reference without being thoroughly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and tried to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to validate publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective score